obdurate
adj
(fml 文) impossible to change; stubborn 固执的; 执拗的
an obdurate refusal 坚决的拒绝
He remained obdurate, refusing to alter his decision. 他依然固执己见, 拒不改变决定.
In the first place, any scientific study requires that there be no preferential weighting of one or another of the items in the series it selects for its consideration.